PATIALA: Researchers on the Indian Institute of Technology (IIT) Ropar, in collaboration with scholars at Ohio State University (US), have developed a generation of painless micro-needles, based on the idea that of mosquito chew, where one does no longer really feel the ache on being bitten.
Based on an idea of mosquito proboscis — tubular mouthparts used for feeding and sucking — the students have known techniques how mosquitoes don't tell us the ache. The use of a numbing agent; a serrated design to the ‘needle’ vibration all the way through the piercing; and a mix of sentimental and hard portions on the proboscis are the strategies for painless needles. However, these needles could be costlier than the ones traditional ones, but might be useful for youngsters and adults.
After reviewing the work already completed about mosquitoes by means of entomologists, researchers used their engineering background and studied the painless piercing means of the mosquitoes. Nano-indentation method used to be used to study and analyze the hardness and stiffness of the tip of the labrum, which is an outer cover of the proboscis. During the research, researchers discovered that labrum used to be softest near the tip and the sides, however it remained harder within the higher part of the labrum. This clicked the idea for a micro-needle that may be drawn or sucked the blood without any ache like a mosquito, because the softer tip might purpose much less ache compared to the harder when it deforms the outside while piercing.
Having a serrated design, like a saw, the fascicle — which is every other part of proboscis in mosquito — proves useful in making insertion easier by means of vibrating, thus lowering the drive had to pierce the outside. Researchers claimed the mosquito’s use of a numbing agent is differently for painless piercing. The mosquito releases saliva once the proboscis is inserted, and the ache is reduced on account of the protein-rich saliva.
The research scholars envision a micro-needle with two needles within. One would in an instant inject a numbing agent, while the second needle would draw the blood or inject the drug. This 2d needle, just like the fascicle of the mosquito, would have a serrated design and be most flexible and softer on the tip and facets. It would additionally vibrate as it is inserted.
The find out about used to be collectively led by means of Bharat Bhushan and Navin Kumar, professor IIT Ropar, while the Ohio State doctoral pupil Dev Gurera may be a co-author. The research paper has been just lately revealed in a world ‘Journal of the Mechanical Behaviour of Biomedical Materials’.
“We took the idea of needles from the mosquito, and it is a new roughly research that will turn out useful for patients who worry piercing, as it will be painless. Till now, we have now best developed a generation, then again no such instrument has been made. In the near long term, we might broaden the instrument or needle based on our generation or we will look out for somebody who could make this instrument,” mentioned Navin.
Based on an idea of mosquito proboscis — tubular mouthparts used for feeding and sucking — the students have known techniques how mosquitoes don't tell us the ache. The use of a numbing agent; a serrated design to the ‘needle’ vibration all the way through the piercing; and a mix of sentimental and hard portions on the proboscis are the strategies for painless needles. However, these needles could be costlier than the ones traditional ones, but might be useful for youngsters and adults.
After reviewing the work already completed about mosquitoes by means of entomologists, researchers used their engineering background and studied the painless piercing means of the mosquitoes. Nano-indentation method used to be used to study and analyze the hardness and stiffness of the tip of the labrum, which is an outer cover of the proboscis. During the research, researchers discovered that labrum used to be softest near the tip and the sides, however it remained harder within the higher part of the labrum. This clicked the idea for a micro-needle that may be drawn or sucked the blood without any ache like a mosquito, because the softer tip might purpose much less ache compared to the harder when it deforms the outside while piercing.
Having a serrated design, like a saw, the fascicle — which is every other part of proboscis in mosquito — proves useful in making insertion easier by means of vibrating, thus lowering the drive had to pierce the outside. Researchers claimed the mosquito’s use of a numbing agent is differently for painless piercing. The mosquito releases saliva once the proboscis is inserted, and the ache is reduced on account of the protein-rich saliva.
The research scholars envision a micro-needle with two needles within. One would in an instant inject a numbing agent, while the second needle would draw the blood or inject the drug. This 2d needle, just like the fascicle of the mosquito, would have a serrated design and be most flexible and softer on the tip and facets. It would additionally vibrate as it is inserted.
The find out about used to be collectively led by means of Bharat Bhushan and Navin Kumar, professor IIT Ropar, while the Ohio State doctoral pupil Dev Gurera may be a co-author. The research paper has been just lately revealed in a world ‘Journal of the Mechanical Behaviour of Biomedical Materials’.
“We took the idea of needles from the mosquito, and it is a new roughly research that will turn out useful for patients who worry piercing, as it will be painless. Till now, we have now best developed a generation, then again no such instrument has been made. In the near long term, we might broaden the instrument or needle based on our generation or we will look out for somebody who could make this instrument,” mentioned Navin.
IIT Ropar researchers use mosquito bite concept to develop painless needles technology
Reviewed by Kailash
on
July 02, 2018
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