NEW DELHI: Doctors at AIIMS have introduced a brand new generation for treating cancers affecting the belly lining, as an example colon cancer or colorectal cancer. It involves administering heated chemotherapy medicine at once into the stomach all through surgery.
Usually, chemotherapy medicine are infused into the veins post-surgery to break cancer cells. With the new generation, doctors mentioned they were ready to deliver higher dosage of chemotherapy medicine.
“It leads to important development in the survival rate of sufferers,” Dr S V S Deo, head of surgical oncology on the institute, told TOI.
The generation referred to as hyperthermic intraperitoneal chemotherapy (HIPEC) has been used on experimental foundation in western international locations for just about two decades. But in India it won flooring simplest not too long ago, mentioned Dr Deo.
At AIIMS, he added, they performed HIPEC for the primary time in 2013 on a 35-year-old lady suffering from peritoneal cancer.
“We weren't sure about the end result then but still went forward as a result of we wanted to save her. The heating of chemotherapy medicine had to be carried out manually and it was once pumped within the patient post-surgery by means of the guts and lung machine. She remains to be alive,” Dr Deo mentioned. The unintentional good fortune was once adopted by way of further trials on nearly 100 sufferers who underwent HIPEC on the institute using the standard machine which has in-built mechanism for heating, temperature regulate and delivery of chemotherapy medicine in cancers involving the peritoneal surface.
“The mortality rate all through surgery has gone down from 10% to 2-Three%. Overall survival rate has advanced by way of 30 to 40% using the new generation,” the head of surgical oncology mentioned.
Some personal hospitals in India additionally be offering HIPEC but it is expensive. AIIMS gives it without spending a dime or at subsidised charges, the doctors mentioned.
They wired on the fact that the generation cannot be used for all cancer sufferers, simplest the ones with cancer affecting belly lining. Also, it needs to be performed at a centre with top skilled and experienced pros given that any variation of drug dosage or temperature regulate may also be fatal. AIIMS not too long ago held a workshop on the institute to coach young surgeons on HIPEC.
Dr Harit Chaturvedi, head of surgical oncology at Max Saket, mentioned they have used HIPEC in 75 circumstances. “The initial effects are encouraging. HIPEC has advanced the outcome in lots of circumstances. However, long term beneficial properties are but to be assessed,” he mentioned.
Colorectal cancer is among the most not unusual cancers in males and its incidence is on the upward thrust mainly on account of bad meals habits. Ovarian cancer is the third most not unusual amongst women. HIPEC, doctors mentioned, might convey hope for plenty of sufferers suffering from them.
Usually, chemotherapy medicine are infused into the veins post-surgery to break cancer cells. With the new generation, doctors mentioned they were ready to deliver higher dosage of chemotherapy medicine.
“It leads to important development in the survival rate of sufferers,” Dr S V S Deo, head of surgical oncology on the institute, told TOI.
The generation referred to as hyperthermic intraperitoneal chemotherapy (HIPEC) has been used on experimental foundation in western international locations for just about two decades. But in India it won flooring simplest not too long ago, mentioned Dr Deo.
At AIIMS, he added, they performed HIPEC for the primary time in 2013 on a 35-year-old lady suffering from peritoneal cancer.
“We weren't sure about the end result then but still went forward as a result of we wanted to save her. The heating of chemotherapy medicine had to be carried out manually and it was once pumped within the patient post-surgery by means of the guts and lung machine. She remains to be alive,” Dr Deo mentioned. The unintentional good fortune was once adopted by way of further trials on nearly 100 sufferers who underwent HIPEC on the institute using the standard machine which has in-built mechanism for heating, temperature regulate and delivery of chemotherapy medicine in cancers involving the peritoneal surface.
“The mortality rate all through surgery has gone down from 10% to 2-Three%. Overall survival rate has advanced by way of 30 to 40% using the new generation,” the head of surgical oncology mentioned.
Some personal hospitals in India additionally be offering HIPEC but it is expensive. AIIMS gives it without spending a dime or at subsidised charges, the doctors mentioned.
They wired on the fact that the generation cannot be used for all cancer sufferers, simplest the ones with cancer affecting belly lining. Also, it needs to be performed at a centre with top skilled and experienced pros given that any variation of drug dosage or temperature regulate may also be fatal. AIIMS not too long ago held a workshop on the institute to coach young surgeons on HIPEC.
Dr Harit Chaturvedi, head of surgical oncology at Max Saket, mentioned they have used HIPEC in 75 circumstances. “The initial effects are encouraging. HIPEC has advanced the outcome in lots of circumstances. However, long term beneficial properties are but to be assessed,” he mentioned.
Colorectal cancer is among the most not unusual cancers in males and its incidence is on the upward thrust mainly on account of bad meals habits. Ovarian cancer is the third most not unusual amongst women. HIPEC, doctors mentioned, might convey hope for plenty of sufferers suffering from them.
AIIMS develops new drug delivery system for cancer
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March 08, 2018
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