SYDNEY: Besides serving to construct strong bones and muscle tissue, Vitamin D may also give protection to center tissue and prevent center failure after a center assault, finds a study carried out on mice.
Heart failure is a life-threatening situation affecting an estimated 23 million other people international.
Vitamin D prevents over the top scarring and thickening of center tissue following a center assault, which might lend a hand cut back the danger of center failure.
"This is a problem because scarring of heart tissue can reduce the heart's ability to pump blood effectively, which can lead to heart failure," stated James Chong, Associate Professor at the Westmead Institute for Medical Research in Australia.
For the study, published within the magazine Heart Lung and Circulation, researchers used mouse models to analyze the impact of 1,25D -- a type of Vitamin D that interacts with hormones -- at the cardiac colony-forming unit fibroblasts (cCFU-Fs)cells that shape scar tissue after a center assault.
Heart attacks happen when blood provide to the center is blocked, leading to tissue injury. This triggers an inflammatory reaction the place the cCFU-Fs substitute the damaged tissue with collagen-based scar tissue.
"Our research shows that vitamin D actually blocks the cCFU-Fs from forming scar tissue. By blocking cCFU-Fs, vitamin D may play an important role in lowering the risk of heart failure after a heart attack," Chong stated.
"The benefits of Vitamin D are becoming increasingly known, but we still don't fully understand how mechanistically it can help with heart disease management. We wanted to know more about how Vitamin D protects the heart after a heart attack," he added.
Heart failure is a life-threatening situation affecting an estimated 23 million other people international.
Vitamin D prevents over the top scarring and thickening of center tissue following a center assault, which might lend a hand cut back the danger of center failure.
"This is a problem because scarring of heart tissue can reduce the heart's ability to pump blood effectively, which can lead to heart failure," stated James Chong, Associate Professor at the Westmead Institute for Medical Research in Australia.
For the study, published within the magazine Heart Lung and Circulation, researchers used mouse models to analyze the impact of 1,25D -- a type of Vitamin D that interacts with hormones -- at the cardiac colony-forming unit fibroblasts (cCFU-Fs)cells that shape scar tissue after a center assault.
Heart attacks happen when blood provide to the center is blocked, leading to tissue injury. This triggers an inflammatory reaction the place the cCFU-Fs substitute the damaged tissue with collagen-based scar tissue.
"Our research shows that vitamin D actually blocks the cCFU-Fs from forming scar tissue. By blocking cCFU-Fs, vitamin D may play an important role in lowering the risk of heart failure after a heart attack," Chong stated.
"The benefits of Vitamin D are becoming increasingly known, but we still don't fully understand how mechanistically it can help with heart disease management. We wanted to know more about how Vitamin D protects the heart after a heart attack," he added.
Vitamin D may cut heart failure risk after heart attack
![Vitamin D may cut heart failure risk after heart attack]()
Reviewed by Kailash
on
March 09, 2018
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